Isolation and Characterization of Dictyostelium Mutants Defective in Sexual Cell Fusion. (Dictyostelium discoideum/sexual cell fusion/fusion-deficient mutants)
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چکیده
منابع مشابه
Cell aggregation and sexual differentiation in pairs of aggregation-deficient mutants of Dictyostelium discoideum.
A diffusible aggregation-stimulating factor (ASF) is released from a series of aggregation-deficient mutants. Biochemical markers indicate that these ASF-donor mutants are blocked at a later step of cell differentiation than an ASF-requiring mutant. ASF is able to bridge the initial block of differentiation in the latter mutant, such that development proceeds up to aggregation and even further....
متن کاملIsolation of germination mutants of Dictyostelium discoideum.
A simple method to separate spores from amoebae of Dictyostelium discoideum has been devized and used to isolate spore germination mutants. A subclass of these mutants is temperature sensitive for germination and growth.
متن کاملDictyostelium mutants lacking the cytoskeletal protein coronin are defective in cytokinesis and cell motility
Coronin is an actin-binding protein in Dictyostelium discoideum that is enriched at the leading edge of the cells and in projections of the cell surface called crowns. The polypeptide sequence of coronin is distinguished by its similarities to the beta-subunits of trimeric G proteins (E. L. de Hostos, B. Bradtke, F. Lottspeich, R. Guggenheim, and G. Gerisch, 1991. EMBO (Eur. Mol. Biol. Organ.) ...
متن کاملDictyostelium Mutants Lacking the Cytoskeletal Protein Coronin Are Defective in Cytokinesis and Cell Motility
Coronin is an actin-binding protein in Dictyostelium discoideum that is enriched at the leading edge of the cells and in projections of the cell surface called crowns. The polypeptide sequence of coronin is distinguished by its similarities to the B-subunits of trimeric G proteins (E. L. de Hostos, B. Bradtke, E Lottspeich, R. Guggenheim, and G. Gerisch. 1991. EMBO (Fur. MoL BioL Organ.)J. 10:4...
متن کاملCytokinesis is defective in Dictyostelium mutants with altered phagocytic recognition, adhesion, and vegetative cell cohesion properties
Mutants that have been selected for defects in phagocytic recognition, adhesion, and vegetative cell-cell cohesion were found to be larger and more highly multinucleate than their parent strain. This defect is associated with the complex mutant phenotype of these mutants since revertants of the mutants coordinately acquire the wild-type phenotype for all of the defects. The larger size and mult...
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ژورنال
عنوان ژورنال: Development, Growth and Differentiation
سال: 1991
ISSN: 0012-1592,1440-169X
DOI: 10.1111/j.1440-169x.1991.00517.x